CAS No.:95-80-7
Name: 2,4-Diaminotoluene
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | subcutaneous | 200mg/kg (200mg/kg) | U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 56, 1941. | |
mouse | LD50 | intraperitoneal | 480mg/kg (480mg/kg) | Journal of Environmental Pathology and Toxicology. Vol. 3(1-2), Pg. 149, 1979. | |
rabbit | LDLo | subcutaneous | 400mg/kg (400mg/kg) | BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Zeitschrift fuer Experimentelle Pathologie und Therapie. Vol. 17, Pg. 59, 1915. |
rat | LD50 | intraperitoneal | 325mg/kg (325mg/kg) | Journal of Environmental Pathology and Toxicology. Vol. 3(1-2), Pg. 149, 1979. | |
rat | LDLo | subcutaneous | 350mg/kg (350mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) CARDIAC: PULSE RATE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION |
Zeitschrift fuer Experimentelle Pathologie und Therapie. Vol. 17, Pg. 59, 1915. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: T, N
Risk Statements: 45-21-25-36-43-51/53
R45:May cause cancer.
R21:Harmful in contact with skin.
R25 :Toxic if swallowed.
R36:Irritating to eyes.
R43:May cause sensitization by skin contact.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 53-45-61
RIDADR: UN 1709 6.1/PG 3
WGK Germany: 3
RTECS: XS9625000
F: 8-10-23
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29215119
Standards and Recommendations:
Analytical Methods:
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