CAS No.:52-51-7
Name: 2-Bromo-2-nitro-1,3-propanediol
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | oral | 250mg/kg (250mg/kg) | "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 30, 1976. | |
| mouse | LD50 | intraperitoneal | 15500ug/kg (15.5mg/kg) | Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 11(1), Pg. 73, 1977. | |
| mouse | LD50 | intravenous | 48mg/kg (48mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 680, 1977. | |
| mouse | LD50 | oral | 270mg/kg (270mg/kg) | Pesticide Manual. Vol. 9, Pg. 103, 1991. | |
| mouse | LD50 | skin | 4750mg/kg (4750mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 680, 1977. | |
| mouse | LD50 | subcutaneous | 116mg/kg (116mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 680, 1977. | |
| rat | LC50 | inhalation | > 5gm/m3/6H (5000mg/m3) | Pesticide Manual. Vol. 9, Pg. 103, 1991. | |
| rat | LD50 | intraperitoneal | 26mg/kg (26mg/kg) | Journal of the Society of Cosmetic Chemists. Vol. 29, Pg. 3, 1978. | |
| rat | LD50 | intravenous | 37400ug/kg (37.4mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 680, 1977. | |
| rat | LD50 | oral | 180mg/kg (180mg/kg) | "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 30, 1976. | |
| rat | LD50 | skin | 1600mg/kg (1600mg/kg) | "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A542, Pg. 1984, | |
| rat | LD50 | subcutaneous | 170mg/kg (170mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 1029, 1974. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes
Xn,
N
Risk Statements 21/22-37/38-41-50
R21/22:Harmful in contact with skin and if swallowed.
R37/38:Irritating to respiratory system and skin.
R41:Risk of serious damage to the eyes.
R50:Very toxic to aquatic organisms.
Safety Statements 26-37/39-61
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39:Wear suitable gloves and eye/face protection.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
Standards and Recommendations:
Analytical Methods:
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