CAS No.:107-41-5

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	2800mg/kg (2800mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: MUSCLE WEAKNESS LIVER: OTHER CHANGES	Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 4, Pg. 142, 1945.
human	TCLo	inhalation	50ppm/15M (50ppm)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 312, 1969.
human	TCLo	inhalation	50ppm (50ppm)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 262, 1946.
mouse	LD50	intraperitoneal	1299mg/kg (1299mg/kg)		Shell Chemical Company. Unpublished Report. Vol. -, Pg. 5, 1961.
mouse	LD50	oral	3097mg/kg (3097mg/kg)		Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 669, 1956.
rabbit	LD50	oral	3200mg/kg (3200mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: MUSCLE WEAKNESS LIVER: OTHER CHANGES	Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 4, Pg. 142, 1945.
rabbit	LD50	skin	8560uL/kg (8.56mL/kg)		"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.
rabbit	LD50	subcutaneous	13gm/kg (13000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Food and Cosmetics Toxicology. Vol. 16, Pg. 777, 1978.
rat	LC50	inhalation	> 310mg/m3/1H (310mg/m3)		BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 12-4/1970,
rat	LD50	oral	3700mg/kg (3700mg/kg)		Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 68, 1974.
rat	LDLo	intraperitoneal	1500mg/kg (1500mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC GASTROINTESTINAL: OTHER CHANGES KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED	Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 150, 1959.

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

 

Standards and Recommendations：

OSHA PEL: CL 25 ppm
ACGIH TLV: CL 25 ppm
DFG MAK: 10 ppm

Analytical Methods：