CAS No.:119-93-7

TOXICITY DATA with REFERENCE：

1.		dns-hmn:hla 1 µmol/L		CNREA8    Cancer Research. 38 (1978),2621.
2.		dns-rat:lvr 1 µmol/L		MUREAV    Mutation Research. 136 (1984),255.
3.		orl-rat TDLo:4500 mg/kg/27D-I:CAR		CNREA8    Cancer Research. 28 (1968),924.
4.		ipr-rat LDLo:125 mg/kg		CBCCT*    “Summary Tables of Biological Tests“ National Research Council Chemical-Biological Coordination Center. 6 (1954),64.
5.		ipr-mus LDLo:125 mg/kg		CBCCT*    “Summary Tables of Biological Tests“ National Research Council Chemical-Biological Coordination Center. 6 (1954),64.

Consensus Reports：

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 1 ,1972,p. 87.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Community Right-To-Know List. Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Hazard Codes: T, N
Risk Statements: 45-68-51/53-22 
R45:May cause cancer. 
R68:Possible risk of irreversible effects. 
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R22:Harmful if swallowed.
Safety Statements: 53-45-61 
S53:Avoid exposure - obtain special instructions before use. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3082 9/PG 3
WGK Germany: 3
RTECS: DD1225000
F: 8
HazardClass: 6.1(b)
PackingGroup: III
Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

Standards and Recommendations：

ACGIH TLV: Animal Carcinogen
DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
NIOSH REL: (o-Toluidine) CL 0.02 mg/m³/60M; avoid skin contact

Analytical Methods：

For occupational chemical analysis use OSHA: #ID-71 or NIOSH: Dyes, 5013.