CAS No.:3732-90-9

TOXICITY DATA with REFERENCE：

Induced tumor data data
Test type: TDLo - Lowest published toxic dose
Route of exposure: Oral
Test species: Rodent - rat
Dose / time: 749 mg/kg/2Y-C
Toxicity: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
Reference: TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 13,257,1985
Test type: TD - Toxic dose (other than lowest)
Route of exposure: Oral
Test species: Rodent - rat
Dose / time: 3900 mg/kg/17W-C
Toxicity: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
Reference: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 19,316,1963
Test type: TD - Toxic dose (other than lowest)
Route of exposure: Oral
Test species: Rodent - rat
Dose / time: 3024 mg/kg/12W-C
Toxicity: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
Reference: VAAZA2 Virchows Archiv, Abteilung B: Cell Pathology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1968- Volume(issue)/page/year: 46,21,1984
Mutation data
Test type: DNA inhibitionTEST SYSTEM : Rodent - rat Liver
Dose / time: 10 umol/L
Reference: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 45,337,1985

Consensus Reports：

 

SAFETY PROFILE：

Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

Standards and Recommendations：

 

Analytical Methods：