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CAS No.:4637-56-3

Name: 4-Hydroxyaminoquinoline-1-oxide

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Details Introduction

TOXICITY DATA with REFERENCE:

1.    

mmo-sat 300 ng/plate

    ENMUDM    Environmental Mutagenesis. 6 (Suppl 2)(1984),1.
2.    

mma-esc 10 µg/plate

    ENMUDM    Environmental Mutagenesis. 6 (Suppl 2)(1984),1.
3.    

dnd-hmn:fbr 10 µmol/L

    BBACAQ    Biochimica et Biophysica Acta. 781 (1984),273.
4.    

dns-hmn:oth 100 nmol/L

    JJIND8    JNCI, Journal of the National Cancer Institute. 69 (1982),557.
5.    

dns-rat-ivn 7 mg/kg

    CBINA8    Chemico-Biological Interactions. 56 (1985),125.
6.    

dnd-ckn:emb 200 µmol/L

    CBINA8    Chemico-Biological Interactions. 47 (1983),123.
7.    

scu-rat TDLo:16 mg/kg/4W-I:CAR

    IGAYAY    Igaku No Ayumi. Progress in Medicine. 120 (1982),1218.
8.    

ivn-rat LDLo:5 mg/kg

    JNCIAM    Journal of the National Cancer Institute. 53 (1974),159.

Consensus Reports:

EPA Genetic Toxicology Program.


SAFETY PROFILE:

A poison by intravenous route. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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