CAS No.:6592-90-1
Name: 5-(1,3-DIMETHYLBUTYL)-5-ETHYL BARBITURIC ACID, SODIUM SALT
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | intravenous | 22mg/kg (22mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939. |
mouse | LD50 | intraperitoneal | 24mg/kg (24mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939. |
mouse | LD50 | subcutaneous | 27mg/kg (27mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939. |
rabbit | LD50 | intravenous | 20mg/kg (20mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939. |
rat | LD50 | subcutaneous | 22mg/kg (22mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939. |
rat | LDLo | intraperitoneal | 10mg/kg (10mg/kg) | Journal of the American Chemical Society. Vol. 58, Pg. 585, 1936. | |
rat | LDLo | parenteral | 10mg/kg (10mg/kg) | Journal of the American Chemical Society. Vol. 58, Pg. 585, 1936. |
Consensus Reports:
SAFETY PROFILE:
Poison by intraperitoneal, subcutaneous, intravenous and parenteral routes. When heated to decomposition it emits toxic fumes of NOx and Na2O. See also BARBITURATES.
Standards and Recommendations:
Analytical Methods:
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