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Current position:Home > Products > 5-(1,3-DIMETHYLBUTYL)-5-ETHYL BARBITURIC ACID, SODIUM SALT

CAS No.:6592-90-1

Name: 5-(1,3-DIMETHYLBUTYL)-5-ETHYL BARBITURIC ACID, SODIUM SALT

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intravenous 22mg/kg (22mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939.
mouse LD50 intraperitoneal 24mg/kg (24mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939.
mouse LD50 subcutaneous 27mg/kg (27mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939.
rabbit LD50 intravenous 20mg/kg (20mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939.
rat LD50 subcutaneous 22mg/kg (22mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 657, 1939.
rat LDLo intraperitoneal 10mg/kg (10mg/kg)   Journal of the American Chemical Society. Vol. 58, Pg. 585, 1936.
rat LDLo parenteral 10mg/kg (10mg/kg)   Journal of the American Chemical Society. Vol. 58, Pg. 585, 1936.


Consensus Reports:

 


SAFETY PROFILE:

Poison by intraperitoneal, subcutaneous, intravenous and parenteral routes. When heated to decomposition it emits toxic fumes of NOx and Na2O. See also BARBITURATES.


Standards and Recommendations:

 


Analytical Methods:

 


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