CAS No.:157-03-9
Name: 6-Diazo-5-oxonorleucine
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
pic-esc 5 µg/plate |
CNREA8 Cancer Research. 43 (1983),2819. | ||
2. |
ipr-rat LD50:80 mg/kg |
CPCHAO Clinical Proceedings of the Childrens Hospital of the District of Columbia. 18 (1962),307. | ||
3. |
orl-mus LD50:197 mg/kg |
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 . | ||
4. |
ipr-mus LDLo:300 mg/kg |
JOENAK Journal of Endocrinology. 18 (1959),204. | ||
5. |
ivn-mus LD50:74 mg/kg |
85ERAY Antibiotics: Origin, Nature, and Properties. 2 (1978),1253. |
Consensus Reports:
EPA Genetic Toxicology Program.
SAFETY PROFILE:
Poison by ingestion, intraperitoneal, and intravenous routes. Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: T
Risk Statements: 23/24/25
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed
Safety Statements: 36/37/39-45
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: RC6340000
F: 8
Standards and Recommendations:
Analytical Methods:
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