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CAS No.:1402-38-6

Name: Actinomycin

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

oms-omi 1250 µg/L

    SOGEBZ    Soviet Genetics. 4 (1968),100.
2.    

cyt-hmn:lym 200 µg/L/2H

    CCPHDZ    Cancer Chemotherapy and Pharmacology. 3 (1979),143.
3.    

orl-rat LDLo:1 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 74 (1942),25.
4.    

ipr-rat LDLo:1 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 74 (1942),25.
5.    

scu-rat LDLo:1 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 74 (1942),25.
6.    

ivn-rat LDLo:1 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 74 (1942),25.
7.    

orl-mus LDLo:10 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 74 (1942),25.
8.    

ipr-mus LDLo:1 mg/kg

    TDKNAF    Takeda Kenkyusho Nempo. Annual Report of the Takeda Research Laboratories. 14 (1955),60.
9.    

scu-mus LDLo:250 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 74 (1942),25.
10.    

ivn-mus LDLo:250 µg/kg

    JPETAB    Journal of Pharmacology an

Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion, intraperitoneal, subcutaneous and intravenous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported.


Standards and Recommendations:

 


Analytical Methods:

 


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