CAS No.:12001-28-4

TOXICITY DATA with REFERENCE：

1.		oms-hmn:fbr 10 mg/L		MUREAV    Mutation Research. 116 (1983),369.
2.		dns-ham:oth 1280 ng/cm2		CNREA8    Cancer Research. 42 (1982),3669.

Consensus Reports：

NTP 10th Report on Carcinogens. IARC Cancer Review: Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 14 (1977),p. 11.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) , IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 2 (1973),p. 17.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 14 (1977),p. 11.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

SAFETY PROFILE：

Confirmed human carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data by inhalation. Human mutation data reported.

Standards and Recommendations：

OSHA PEL: TWA 2 million fibers/m³; CL 10 million fibers/m³; Cancer Hazard
ACGIH TLV: TWA 0.1 fibers/cc; Confirmed Human Carcinogen
DFG MAK: DFG TRK: (Fine dust particles that are able to reach the alveolar area of the lung) crocidolite: 0.05 × 10⁶ fibers/m³ (0.025 mg/m³) (definition of fiber: length greater than 5 µm; diameter less than 3 µm; length/diameter greater than 3:1, equivalent to 1 fiber/cc)
NIOSH REL: (asbestos): 0.1 fb/cc in a 400 L air sample
DOT Classification:  9; Label: CLASS 9

Analytical Methods：

For occupational chemical analysis use NIOSH: Fibers, 7400; Asbestos Fibers, 7402.