CAS No.:37661-08-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	176mg/kg (176mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Chemotherapy Vol. 27(Suppl,
mouse	LD50	intravenous	184mg/kg (184mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Chemotherapy Vol. 27(Suppl,
mouse	LD50	oral	8529mg/kg (8529mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Chemotherapy Vol. 27(Suppl,
mouse	LD50	subcutaneous	9475mg/kg (9475mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Chemotherapy Vol. 27(Suppl,
rat	LD50	intravenous	176mg/kg (176mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Chemotherapy Vol. 27(Suppl,
rat	LD50	oral	10gm/kg (10000mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1735, 1981.
rat	LD50	subcutaneous	10gm/kg (10000mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1735, 1981.

Consensus Reports：

 

SAFETY PROFILE：

Poison by intraperitoneal and intravenous routes. Mildly toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NO_x, SO_x, and HCl.

Standards and Recommendations：

 

Analytical Methods：