CAS No.:73-48-3

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	4800mg/kg (4800mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 238, Pg. 435, 1960.
mouse	LD50	intravenous	395mg/kg (395mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 273, 1961.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)		Drugs in Japan Vol. 6, Pg. 781, 1982.
women	TDLo	oral	300ug/kg/3D-I (0.3mg/kg)		Lancet. Vol. 2, Pg. 634, 1986.

Consensus Reports：

 

SAFETY PROFILE：

Poison by intravenous route. Human systemic effects by ingestion: convulsions and somnolence. Mutation data reported. When heated to decomposition it emits toxic fumes of F⁻, SO_x, and NO_x.

Standards and Recommendations：

 

Analytical Methods：