CAS No.:471-03-4

TOXICITY DATA with REFERENCE：

Toxic information about Bis(2-Chloroethyl)Sulfone (CAS NO.471-03-4) is:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LCLo	inhalation	1430mg/m3/10M (1430mg/m3)		National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. NDCrc-132, Pg. JAN1942,
mouse	LC	inhalation	> 1gm/m3/10M (1000mg/m3)		National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. NDCrc-132, Pg. Jan, 1942.
mouse	LD50	intravenous	50mg/kg (50mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
mouse	LD50	subcutaneous	35mg/kg (35mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
rabbit	LCLo	inhalation	1430mg/m3/10M (1430mg/m3)		National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. NDCrc-132, Pg. JAN1942,
rat	LD50	intravenous	> 72mg/kg (72mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
rat	LD50	subcutaneous	50mg/kg (50mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
rat	LDLo	unreported	80mg/kg (80mg/kg)		Gann. Japanese Journal of Cancer Research. Vol. 43, Pg. 171, 1952.

Consensus Reports：

 

SAFETY PROFILE：

A poison via intravenous and subcutaneous routes. Moderately toxic via inhalation. See also SULFONATES. When heated to decomposition it emits very toxic fumes of Cl⁻ and SO_x.

Standards and Recommendations：

 

Analytical Methods：