CAS No.:35763-44-1
Name: Butobarbital sodium
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LDLo | intraperitoneal | 275mg/kg (275mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 31, Pg. 455, 1927. | |
rat | LD50 | intraperitoneal | 197mg/kg (197mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
rat | LDLo | subcutaneous | 80mg/kg (80mg/kg) | BEHAVIORAL: SLEEP | Journal of Pharmacology and Experimental Therapeutics. Vol. 60, Pg. 323, 1937. |
Consensus Reports:
SAFETY PROFILE:
Poison by intraperitoneal and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx and Na2O. See also BARBITURATES.
Standards and Recommendations:
Analytical Methods:
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