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Current position:Home > Products > Cefaloglycin

CAS No.:3577-01-3

Name: Cefaloglycin

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1030mg/kg (1030mg/kg) kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)" Chemotherapy Vol. 18, Pg. 22, 1970.
mouse LD50 oral > 10gm/kg (10000mg/kg) liver: other changes Chemotherapy Vol. 18, Pg. 22, 1970.
mouse LD50 subcutaneous 3700mg/kg (3700mg/kg) kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)" Chemotherapy Vol. 18, Pg. 22, 1970.
rat LD50 intraperitoneal 1300mg/kg (1300mg/kg) kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)" Chemotherapy Vol. 18, Pg. 22, 1970.
rat LD50 oral > 10gm/kg (10000mg/kg) liver: other changes Chemotherapy Vol. 18, Pg. 22, 1970.
rat LD50 subcutaneous 2800mg/kg (2800mg/kg) kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)" Chemotherapy Vol. 18, Pg. 22, 1970.

Consensus Reports:

 


SAFETY PROFILE:

Moderately toxic by subcutaneous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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