CAS No.:541-25-3

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LCLo	inhalation	50gm/m3/30M (50000mg/m3)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Reviews of Environmental Contamination and Toxicology. Vol. 110, Pg. 75, 1989.
dog	LD50	intravenous	2mg/kg (2mg/kg)		National Technical Information Service. Vol. PB158-508,
dog	LD50	skin	15mg/kg (15mg/kg)		Journal of Pathology and Bacteriology. Vol. 58, Pg. 411, 1946.
dog	LD50	subcutaneous	2mg/kg (2mg/kg)		Journal of Pathology and Bacteriology. Vol. 58, Pg. 411, 1946.
domestic animals - goat/sheep	LD50	skin	10mg/kg (10mg/kg)		National Technical Information Service. Vol. PB158-508,
guinea pig	LD50	skin	12mg/kg (12mg/kg)		Journal of Pathology and Bacteriology. Vol. 58, Pg. 411, 1946.
guinea pig	LD50	subcutaneous	1mg/kg (1mg/kg)		Journal of Pathology and Bacteriology. Vol. 58, Pg. 411, 1946.
guinea pig	LDLo	intraperitoneal	2mg/kg (2mg/kg)		National Technical Information Service. Vol. PB158-508,
human	LCLo	inhalation	6ppm/30M (6ppm)		National Technical Information Service. Vol. PB214-270,
human	LDLo	skin	37600ug/kg (37.6mg/kg)		EHP, Environmental Health Perspectives. Vol. 98, Pg. 259, 1992.
mouse	LD50	skin	12mg/kg (12mg/kg)		National Technical Information Service. Vol. PB158-508,
rabbit	LD50	intravenous	500ug/kg (0.5mg/kg)		Journal of Pathology and Bacteriology. Vol. 58, Pg. 411, 1946.
rabbit	LD50	skin	4mg/kg (4mg/kg)		Biochemical Journal. Vol. 41, Pg. 325, 1947.
rabbit	LD50	subcutaneous	2mg/kg (2mg/kg)		Journal of Pathology and Bacteriology. Vol. 58, Pg. 411, 1946.
rat	LD50	oral	50mg/kg (50mg/kg)		EHP, Environmental Health Perspectives. Vol. 98, Pg. 259, 1992.
rat	LD50	skin	15mg/kg (15mg/kg)		National Technical Information Service. Vol. PB158-508,
rat	LD50	subcutaneous	1mg/kg (1mg/kg)		Journal of Pathology and Bacteriology. Vol. 58, Pg. 411, 1946.

 

Consensus Reports：

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List. Arsenic and its compounds are on the Community Right-To-Know List.

SAFETY PROFILE：

A human poison by inhalation. Poison experimentally by inhalation, skin contact, subcutaneous, intraperitoneal, and intravenous routes. An experimental teratogen. A blistering-type military poison. Lewisite is absorbed through skin; as little as 2 mL on the skin can cause death. Has a delayed action similar to distilled mustard gas. This gas exhibits a systemic poisoning effect on humans. When Chlorovinylarsine dichloride (CAS NO.541-25-3) is heated to decomposition, it emits toxic fumes of Cl⁻ and As. See also ARSENIC COMPOUNDS.

RIDADR 2927
HazardClass 6.1(a)
PackingGroup I

Standards and Recommendations：

 

Analytical Methods：