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CAS No.:1215-83-4

Name: Clobutinol hydrochloride

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Details Introduction

TOXICITY DATA with REFERENCE:

1.    

orl-rat LD50:802 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),241.
2.    

ipr-rat LD50:151 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),241.
3.    

scu-rat LD50:702 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),241.
4.    

ivn-rat LD50:63 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),241.
5.    

orl-mus LD50:334 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),241.
6.    

ipr-mus LD50:125 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),241.
7.    

scu-mus LD50:262 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 4 (1970),961.
8.    

ivn-mus LD50:40,900 µg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),241.
9.    

ivn-dog LD50:45,300 


Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An antitussive. When heated to decomposition it emits toxic fumes of Cl and NOx. See also ALCOHOL, DENATURED; ALCOHOLS, C6-12; ALCOHOLS, C9-11; ALCOHOLS, C12-13, ETHOXYLATED; ALCOHOLS, C12-15, ETHOXYLATED; ALCOHOLS, C12-16, ETHOXYLATED; ALCOHOLS, C14-15, ETHOXYLATED; ALCOHOLS, C16-18, ETHOXYLATED; ALCOHOLS, C8-10, ETHOXYLATED PROPOXYLATED; ALCOHOLS, C12-15, ETHOXYLATED PROPOXYLATED; ALCOHOLS, N.O.S..


Standards and Recommendations:

 


Analytical Methods:

 


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