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CAS No.:

Name: DIMEBON DIHYDROCHLORIDE

Details Introduction

TOXICITY DATA with REFERENCE:

1.   

orl-rat LD50:1132 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 48 (1985),103.
2.   

ipr-rat LD50:160 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 48 (1985),103.
3.   

ivn-rat LD50:59 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 48 (1985),103.
4.   

orl-mus LD50:486 mg/kg

    FATOAO    Farmakologiya i Toksikologiya (Moscow). 47 (3)(1984),75.
5.   

ipr-mus LD50:145 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 48 (1985),103.
6.   

scu-mus LD50:465 mg/kg

    FATOAO    Farmakologiya i Toksikologiya (Moscow). 47 (3)(1984),75.
7.   

ivn-mus LD50:90,500 µg/kg

    FATOAO    Farmakologiya i Toksikologiya (Moscow). 47 (3)(1984),75.

SAFETY PROFILE:
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx and HCl.

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