CAS No.:8015-54-1

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intravenous	45mg/kg (45mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 224, 1972.
human	TDLo	intramuscular	100ug/kg (0.1mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	"Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents," National Research Council, 3 vols., Washington, DC, National Academy Press, 1982-85Vol. 1, Pg. L1, 1982.
human	TDLo	oral	40ug/kg (0.04mg/kg)	SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Nervous and Mental Disease. Vol. 131, Pg. 428, 1960.
man	TDLo	intramuscular	150ug/kg (0.15mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 32, Pg. 250, 1973.
mouse	LD50	intraperitoneal	60mg/kg (60mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 224, 1972.
mouse	LD50	intravenous	10mg/kg (10mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 224, 1972.
mouse	LD50	oral	300mg/kg (300mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: EXCITEMENT BEHAVIORAL: IRRITABILITY	Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 1727, 1971.
rabbit	LD50	intravenous	12mg/kg (12mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 224, 1972.
rat	LD50	intraperitoneal	25mg/kg (25mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 224, 1972.
rat	LD50	intravenous	19mg/kg (19mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 224, 1972.

Consensus Reports：

 

SAFETY PROFILE：

Poison by intravenous, intraperitoneal, and intramuscular routes. Human systemic effects by ingestion and intramuscular routes: visual field changes, hallucinations, distorted perceptions, nausea and vomiting. When DITRAN (CAS NO.8015-54-1) is heated to decomposition, it emits toxic fumes of NO_x and Cl⁻.

Standards and Recommendations：

 

Analytical Methods：