CAS No.:617-48-1
Name: DL-Malic acid
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 50mg/kg (50mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4937, 1982. | |
mouse | LD50 | oral | 1600mg/kg (1600mg/kg) | Kodak Company Reports. Vol. #82-0458, | |
rat | LD50 | intraperitoneal | 100mg/kg (100mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4937, 1982. |
CAS# 6915-15-7: Draize test, rabbit, eye: 750 ug/24H Severe;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Oral, mouse: LD50 = 1600 mg/kg;
Carcinogenicity: DL-Malic acid - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Other: The toxicological properties have not been fully investigated. See actual entry in RTECS for complete information.
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: Xn
Risk Statements: 22-37/38-41-42/43-34
R22: Harmful if swallowed
R37/38: Irritating to respiratory system and skin
R41: Risk of serious damage to the eyes
R42/43: May cause sensitization by inhalation and skin contact
R34: Causes burns
Safety Statements: 26-39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S39: Wear eye / face protection
WGK Germany: 1
RTECS: ON7175000
Standards and Recommendations:
Analytical Methods:
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