CAS No.:81-13-0
Name: Dexpanthenol
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
skn-rbt 500 mg/4H MLD |
JACTDZ Journal of the American College of Toxicology. 6 (1)(1987),139. | ||
2. |
eye-rbt 500 µg MLD |
JACTDZ Journal of the American College of Toxicology. 6 (1)(1987),139. | ||
3. |
orl-mus LD50:15 g/kg |
JACTDZ Journal of the American College of Toxicology. 6 (1)(1987),139. | ||
4. |
ipr-mus LD50:9 g/kg |
FRPSAX Farmaco, Edizione Scientifica. 14 (1959),43. | ||
5. |
ivn-mus LD50:7000 mg/kg |
NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),599. | ||
6. |
ivn-rbt LD50:4000 mg/kg |
NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),599. |
Consensus Reports:
Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Hazard Codes: Xn
Risk Statements: 36/37/38-48-41-37/38-20/21/22
R36/37/38:Irritating to eyes, respiratory system and skin.
R48:Danger of serious damage to health by prolonged exposure.
R41:Risk of serious damage to the eyes.
R37/38:Irritating to respiratory system and skin.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 23-24/25-45-36/37/39-26-22
S23:Do not breathe vapour.
S24/25:Avoid contact with skin and eyes.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S22:Do not breathe dust.
WGK Germany: 1
RTECS: ES4316000
F: 3-10
Moderately toxic by intravenous route. A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES.
Standards and Recommendations:
Analytical Methods:
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