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CAS No.:81-13-0

Name: Dexpanthenol

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Details Introduction

TOXICITY DATA with REFERENCE:

1.    

skn-rbt 500 mg/4H MLD

    JACTDZ    Journal of the American College of Toxicology. 6 (1)(1987),139.
2.    

eye-rbt 500 µg MLD

    JACTDZ    Journal of the American College of Toxicology. 6 (1)(1987),139.
3.    

orl-mus LD50:15 g/kg

    JACTDZ    Journal of the American College of Toxicology. 6 (1)(1987),139.
4.    

ipr-mus LD50:9 g/kg

    FRPSAX    Farmaco, Edizione Scientifica. 14 (1959),43.
5.    

ivn-mus LD50:7000 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),599.
6.    

ivn-rbt LD50:4000 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),599.

Consensus Reports:

Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Hazard Codes: HarmfulXn
Risk Statements: 36/37/38-48-41-37/38-20/21/22 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R48:Danger of serious damage to health by prolonged exposure. 
R41:Risk of serious damage to the eyes. 
R37/38:Irritating to respiratory system and skin. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 23-24/25-45-36/37/39-26-22 
S23:Do not breathe vapour. 
S24/25:Avoid contact with skin and eyes. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S22:Do not breathe dust.
WGK Germany: 1
RTECS: ES4316000
F: 3-10
Moderately toxic by intravenous route. A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES.


Standards and Recommendations:

 


Analytical Methods:

 


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