CAS No.:117-84-0
Name: Dioctyl phthalate
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | skin | > 5gm/kg (5000mg/kg) | "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1906, 1963. | |
mouse | LD50 | intraperitoneal | 65gm/kg (65000mg/kg) | Journal of the Society of Cosmetic Chemists. Vol. 28, Pg. 667, 1977. | |
mouse | LD50 | oral | 6513mg/kg (6513mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 17(11), Pg. 51, 1973. | |
rat | LD50 | intraperitoneal | > 50mL/kg (50mL/kg) | Journal of Pharmaceutical Sciences. Vol. 61, Pg. 51, 1972. | |
rat | LD50 | oral | 47gm/kg (47000mg/kg) | Farmakologiya i Toksikologiya Vol. 39, Pg. 635, 1976. |
Consensus Reports:
n-Dioctyl phthalate's reported in EPA TSCA Inventory.
SAFETY PROFILE:
Mildly toxic by ingestion. Experimental teratogenic and reproductive effects. A skin and severe eye irritant. Used as a plasticizer. When heated to decomposition it emits acrid smoke and irritating fumes.
Risk Statements: 60-61
R60:May impair fertility.
R61:May cause harm to the unborn child.
Safety Statements: 23-24/25
S23:Do not breathe vapour.
S24/25:Avoid contact with skin and eyes.
RIDADR: 2810
WGK Germany: 2
RTECS: TI1925000
Standards and Recommendations:
Analytical Methods:
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