CAS No.:82159-09-9
Name: Epalrestat
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | oral | > 1gm/kg (1000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. | |
mouse | LD50 | intraperitoneal | 687mg/kg (687mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. | |
mouse | LD50 | intravenous | 255ug/kg (0.255mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. | |
mouse | LD50 | oral | 3200mg/kg (3200mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. | |
mouse | LD50 | subcutaneous | > 3gm/kg (3000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. | |
rat | LD50 | intraperitoneal | 922gm/kg (922000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. | |
rat | LD50 | intravenous | 255ug/kg (0.255mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. | |
rat | LD50 | oral | 5300ug/kg (5.3mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. | |
rat | LD50 | subcutaneous | > 3gm/kg (3000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992. |
Consensus Reports:
SAFETY PROFILE:
Standards and Recommendations:
Analytical Methods:
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