CAS No.:56420-45-2
Name: Epirubicin
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | 2mg/kg (2mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING |
Toxicology and Applied Pharmacology. Vol. 79, Pg. 412, 1985. |
| mouse | LD50 | intravenous | 16070ug/kg (16.07mg/kg) | Toxicology and Applied Pharmacology. Vol. 79, Pg. 412, 1985. | |
| mouse | LD50 | unreported | 29300ug/kg (29.3mg/kg) | Biochemical Pharmacology. Vol. 38, Pg. 167, 1989. | |
| rabbit | LDLo | intrapleural | 400ug/kg (0.4mg/kg) | CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: "FIBROSIS, FOCAL (PNEUMOCONIOSIS)" LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA |
Pharmacology and Toxicology Vol. 62, Pg. 84, 1988. |
| rat | LD50 | intravenous | 14270ug/kg (14.27mg/kg) | Toxicology and Applied Pharmacology. Vol. 79, Pg. 412, 1985. |
Consensus Reports：
SAFETY PROFILE：
Standards and Recommendations：
Analytical Methods：
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