CAS No.:563-12-2

TOXICITY DATA with REFERENCE：

1.		orl-inf TDLo:15,700 µg/kg:CNS,PNS,MET		TXMDAX    Texas Medicine. 63 (1967),71.
2.		orl-hmn TDLo:100 µg/kg:BIO		TXAPA9    Toxicology and Applied Pharmacology. 22 (1972),286.
3.		orl-rat LD50:13 mg/kg		PHJOAV    Pharmaceutical Journal. 185 (1960),361.
4.		ihl-rat LC50:864 mg/m3		FMCHA2    Farm Chemicals Handbook .(Meister Publishing,Willoughy, OH.: )1991,C128.
5.		skn-rat LD50:62 mg/kg		TXAPA9    Toxicology and Applied Pharmacology. 14 (1969),515.
6.		ipr-rat LD50:26 mg/kg		PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 129 (1968),699.
7.		orl-mus LD50:40 mg/kg		85DPAN    Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel Werner Perkow,Berlin, Germany.: Verlag Paul Parey,1971/76.
8.		ipr-mus LD50:35 mg/kg		PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 129 (1968),699.
9.		skn-rbt LD50:890 mg/kg		TobJS#    Personal Communication to the Editor, Toxic Substances List from Dr. J.S. Tobin, Director, Health and Safety, FMC Corporation, New York, NY 14103, November 9, 1973 9NOV73 .

Consensus Reports：

EPA: Farm Worker Field Reentry FEREAC    Federal Register. 39 (1974),16888. . EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List.

SAFETY PROFILE：

Poison by ingestion, skin contact, and intraperitoneal routes. Human systemic effects by ingestion: flaccid paralysis without anesthesia, motor activity changes, fever, and inhibition of cholinesterase. When heated to decomposition it emits highly toxic fumes of SO_x and PO_x. See also PARATHION.

Standards and Recommendations：

OSHA PEL: TWA 0.4 mg/m³ (skin)
ACGIH TLV: TWA 0.05 mg/m³ (skin); Not Classifiable as a Human Carcinogen

Analytical Methods：