CAS No.:63516-07-4
Name: Flutropium bromide
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 53mg/kg (53mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988. | |
mouse | LD50 | intravenous | 11mg/kg (11mg/kg) | behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea behavioral: ataxia | Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986. |
mouse | LD50 | oral | 760mg/kg (760mg/kg) | behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: dyspnea | Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986. |
mouse | LD50 | subcutaneous | 228mg/kg (228mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988. | |
rat | LD50 | intraperitoneal | 77mg/kg (77mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988. | |
rat | LD50 | intravenous | 12500ug/kg (12.5mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988. | |
rat | LD50 | oral | 740mg/kg (740mg/kg) | behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: dyspnea | Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986. |
rat | LD50 | subcutaneous | 615mg/kg (615mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988. |
Consensus Reports:
SAFETY PROFILE:
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx, Br−, and Cl−.
Standards and Recommendations:
Analytical Methods:
Related Searches
Other Product
- -
- -
- -
- -
- -
- -
- -
- -
- -
- (4S,6R)-6-{2-[(2-hydroxy-ethyl)-(4-methoxy-benzenesulfonyl)-amino]-ethoxy}-4-isopropyl-5,6-dihydro-4H-pyran-2-carboxylic acid allyl ester
- [1,4'-Bipiperidine]-1'-carboxylic acid, 4-(1H-indol-7-yl)-, ethyl ester
- 1,3,5-Tris(4-acetamidophenyl)penta-1,5-dione
- 1,5-Bis(3-aminophenyl)-3-(4-N,N-di-methylaminophenyl)penta-1,5-dione
- 1,5-Bis(4-acetamidophenyl)-3-phenylpenta-1,5-dione
- 1,5-Bis(4-aminophenyl)-3-(4-acetamido-phenyl)penta-1,5-dione
- 1,5-Bis(4-aminophenyl)-3-phenylpenta-1,5-dione