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Current position:Home > Products > Flutropium bromide

CAS No.:63516-07-4

Name: Flutropium bromide

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 53mg/kg (53mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
mouse LD50 intravenous 11mg/kg (11mg/kg) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea behavioral: ataxia Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
mouse LD50 oral 760mg/kg (760mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: dyspnea Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
mouse LD50 subcutaneous 228mg/kg (228mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat LD50 intraperitoneal 77mg/kg (77mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat LD50 intravenous 12500ug/kg (12.5mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat LD50 oral 740mg/kg (740mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: dyspnea Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
rat LD50 subcutaneous 615mg/kg (615mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.

Consensus Reports:

 


SAFETY PROFILE:

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx, Br, and Cl.


Standards and Recommendations:

 


Analytical Methods:

 


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