CAS No.:67-45-8
Name: Furazolidone
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
pic-esc 2 mg/L |
MUREAV Mutation Research. 156 (1985),69. | ||
2. |
cyt-hmn:lym 2 mg/L/72H |
MUREAV Mutation Research. 59 (1979),139. | ||
3. |
orl-man TDLo:11 mg/kg:PUL,BLD |
ARDSBL American Review of Respiratory Disease. 105 (1972),823. | ||
4. |
orl-rat LD50:2336 mg/kg |
TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. | ||
5. |
orl-mus LD50:1782 mg/kg |
TRSTAZ Transactions of the Royal Society of Tropical Medicine and Hygiene. 74 (1980),43. | ||
6. |
ipr-mus LD50:300 mg/kg |
PMDCAY Progress in Medical Chemistry. 5 (1967),320. | ||
7. |
orl-ckn LDLo:150 mg/kg CLDND* |
Consensus Reports:
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 31 ,1983,p. 141.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
SAFETY PROFILE:
Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: dyspnea, respiratory depression, and eosinophilia. Experimental reproductive effects. Human mutation data reported. Questionable carcinogen. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: Xn
Risk Statements: 62-40
R62:Risk of impaired fertility.
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 36-22
S36:Wear suitable protective clothing.
S22:Do not breathe dust.
WGK Germany: 3
Standards and Recommendations:
Analytical Methods:
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