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CAS No.:2752-65-0

Name: Gambogic acid

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 unreported 55mg/kg (55mg/kg)   "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai Science/Technology Publisher,Peop. Rep. China, 1994Vol. -, Pg. 220, 1994.
mouse LD50 subcutaneous 354mg/kg (354mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 8(1), Pg. 331, 1982.
rat LD50 intraperitoneal 88mg/kg (88mg/kg)
liver: other changes
Indian Journal of Experimental Biology. Vol. 5, Pg. 96, 1967.
rat LD50 intravenous 107mg/kg (107mg/kg)
liver: other changes
Indian Journal of Experimental Biology. Vol. 5, Pg. 96, 1967.

Consensus Reports:

 


SAFETY PROFILE:

Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and fumes.


Standards and Recommendations:

 


Analytical Methods:

 


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