CAS No.:72590-77-3
Name: Hydrocortisone buteprate
Details Introduction
TOXICITY DATA with REFERENCEļ¼
| 1. |
skn-rbt 1000 ppm MLD |
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (1981),3023. | ||
| 2. |
orl-rat LD50:5120 mg/kg |
JTSCDR Journal of Toxicological Sciences. 6 (Suppl)(1981),1. | ||
| 3. |
ipr-rat LD50:1420 mg/kg |
JTSCDR Journal of Toxicological Sciences. 6 (Suppl)(1981),1. | ||
| 4. |
scu-rat LD50:3260 mg/kg |
JTSCDR Journal of Toxicological Sciences. 6 (Suppl)(1981),1. | ||
| 5. |
orl-mus LD50:6720 mg/kg |
JTSCDR Journal of Toxicological Sciences. 6 (Suppl)(1981),1. | ||
| 6. |
ipr-mus LD50:1660 mg/kg |
JTSCDR Journal of Toxicological Sciences. 6 (Suppl)(1981),1. | ||
| 7. |
scu-mus LD50:1980 mg/kg |
JTSCDR Journal of Toxicological Sciences. 6 (Suppl)(1981),1. |
SAFETY PROFILEļ¼
Moderately toxic by subcutaneous and intraperitoneal routes. Mildly toxic by ingestion. Experimental reproductive effects. An experimental teratogen. A skin irritant. A steroid. When heated to decomposition it emits toxic fumes. See also HYDROCORTISONE-21-ACETATE; HYDROCORTISONE-17-BUTYRATE; HYDROCORTISONE-21-PHOSPHATE; HYDROCORTISONE SODIUM SUCCINATE.
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