CAS No.:118-42-3
Name: Hydroxychloroquine
Details Introduction
TOXICITY DATA with REFERENCE:
| 1. |
orl-mus LD50:1240 mg/kg |
JMCMAR Journal of Medicinal Chemistry. 12 (1969),184. | ||
| 2. |
orl-hmn TDLo:429 mg/kg/25D:SKN,BLD |
LANCAO Lancet. 1 (1965),1275. | ||
| 3. |
orl-man TDLo:600 mg/kg/25D:GIT |
34ZIAG Toxicology of Drugs and Chemicals Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,321. |
SAFETY PROFILE:
Moderately toxic by ingestion. Human systemic effects by ingestion: dermatitis, gastritis, angranulocytosis. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
Side effects: abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting.
Overdose symptoms:convulsions, drowsiness, headache, heart problems or heart failure, difficulty breathing and vision problems.
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