CAS No.:96-84-4
Name: Iophenoxic acid
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intravenous | 203mg/kg (203mg/kg) | CARDIAC: PULSE RATE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953. |
guinea pig | LD50 | intraperitoneal | 570mg/kg (570mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953. |
mouse | LD50 | intraperitoneal | 440mg/kg (440mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953. |
mouse | LD50 | intravenous | 374mg/kg (374mg/kg) | Journal of Medicinal Chemistry. Vol. 13, Pg. 997, 1970. | |
mouse | LD50 | oral | 1850mg/kg (1850mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953. |
rat | LD50 | intraperitoneal | 648mg/kg (648mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953. |
rat | LD50 | oral | 2gm/kg (2000mg/kg) | Pharmazie. Vol. 12, Pg. 315, 1957. |
Consensus Reports:
SAFETY PROFILE:
Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of I−.
Hazard Codes Xn
Risk Statements 22-36/37/38
R22: Iophenoxic acid (CAS NO.96-84-4) is harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39: When Iophenoxic acid (CAS NO.96-84-4) is used ,wear suitable gloves and eye/face protection.
WGK Germany 3
RTECS MW5280000
Standards and Recommendations:
Analytical Methods:
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