CAS No.:42509-80-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
hamster	LD50	oral	66mg/kg (66mg/kg)		Ciba-Geigy Toxicology Data/Indexes.
mouse	LD50	oral	34mg/kg (34mg/kg)		Ciba-Geigy Toxicology Data/Indexes.
rabbit	LD50	oral	175mg/kg (175mg/kg)	BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	National Technical Information Service. Vol. OTS0535376,
rabbit	LD50	skin	755mg/kg (755mg/kg)		Ciba-Geigy Toxicology Data/Indexes.
rat	LC50	inhalation	103mg/m3/4H (103mg/m3)		National Technical Information Service. Vol. OTS0535364,
rat	LD50	intraperitoneal	36mg/kg (36mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	National Technical Information Service. Vol. OTS0538007,
rat	LD50	oral	27mg/kg (27mg/kg)	SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA	National Technical Information Service. Vol. OTS0535938,
rat	LD50	skin	118mg/kg (118mg/kg)		Pesticide Manual. Vol. 9, Pg. 502, 1991.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion, inhalation, and skin contact. Used as a pesticide against pathogenic root nematodes on bananas, citrus, and various annual crops. When heated to decomposition it emits very toxic fumes of Cl⁻, NO_x, PO_x, and SO_x. See also ESTERS.
Safety Information of Isazofos (CAS NO.42509-80-8):
Hazard Codes: T+,N
Risk Statements: 24/25-26-43-48/20-50/53 
20:  Harmful by inhalation 
24:  Toxic in contact with skin 
25:  Toxic if swallowed 
26:  Very Toxic by inhalation 
43:  May cause sensitization by skin contact 
48:  Danger of serious damage to health by prolonged exposure 
50:  Very Toxic to aquatic organisms 
53:  May cause long-term adverse effects in the aquatic environment 
Safety Statements: 28-36/37-38-45-59-61
28:  After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
38:  In case of insufficient ventilation, wear suitable respiratory equipment 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
59:  Refer to manufacturer/supplier for information on recovery/recycling 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 

Standards and Recommendations：

 

Analytical Methods：