CAS No.:59-63-2

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 40mg/kg (40mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Annals of the New York Academy of Sciences. Vol. 80, Pg. 626, 1959.
monkey	LD50	oral	160mg/kg (160mg/kg)		Annals of the New York Academy of Sciences. Vol. 80, Pg. 626, 1959.
mouse	LD50	intraperitoneal	138mg/kg (138mg/kg)		Journal of Medicinal and Pharmaceutical Chemistry. Vol. 2, Pg. 133, 1960.
mouse	LD50	oral	193mg/kg (193mg/kg)		Annals of the New York Academy of Sciences. Vol. 80, Pg. 626, 1959.
mouse	LD50	subcutaneous	150mg/kg (150mg/kg)		Toxicology and Applied Pharmacology. Vol. 39, Pg. 141, 1977.
rat	LD50	intraperitoneal	199mg/kg (199mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 240, 1972.
rat	LD50	oral	280mg/kg (280mg/kg)		Annals of the New York Academy of Sciences. Vol. 80, Pg. 626, 1959.
women	TDLo	oral	4800ug/kg/21W (4.8mg/kg)		Journal of Clinical Pyschopharmacology. Vol. 3, Pg. 42, 1983.
women	TDLo	oral	4800ug/kg/21W (4.8mg/kg)		Journal of Clinical Pyschopharmacology. Vol. 3, Pg. 42, 1983.

Consensus Reports：

 

SAFETY PROFILE：

A poison by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects: monoamine oxidase effects. Mutation data reported. A pharmaceutical and veterinary drug. When Isocarboxazid (CAS NO.59-63-2) is heated to decomposition, it emits toxic fumes of NO_x.

RIDADR 3249
HazardClass 6.1(b)
PackingGroup III

Standards and Recommendations：

 

Analytical Methods：