CAS No.:4350-09-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	298mg/kg (298mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 307, 1975.
mouse	LD50	intravenous	375mg/kg (375mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA BEHAVIORAL: EXCITEMENT	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 523, 1973.
mouse	LD50	oral	1708mg/kg (1708mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 307, 1975.
mouse	LD50	subcutaneous	418mg/kg (418mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 307, 1975.
rabbit	LD50	oral	285mg/kg (285mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 307, 1975.
rat	LD50	intraperitoneal	91mg/kg (91mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT BEHAVIORAL: ATAXIA	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 523, 1973.
rat	LD50	intravenous	27mg/kg (27mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 307, 1975.
rat	LD50	oral	243mg/kg (243mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT BEHAVIORAL: ATAXIA	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 523, 1973.
rat	LD50	subcutaneous	149mg/kg (149mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 307, 1975.

Consensus Reports：

 

SAFETY PROFILE：

Safety Information of L-5-Hydroxytryptophan (CAS NO.4350-09-8):
Hazard Codes: XnXi
Risk Statements: 22-36/37/38-65-20/21/22-20/21
 R22: Harmful if swallowed. 
R36/37/38: Irritating to eyes, respiratory system and skin. 
R65: Harmful: may cause lung damage if swallowed. 
R20/21: Harmful by inhalation and in contact with skin.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 36-26
S36:Wear suitable protective clothing. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: YN7110000
HazardClass: 6.1
PackingGroup: III
HS Code: 29339990

Standards and Recommendations：

 

Analytical Methods：