CAS No.:64953-12-4
Name: Latamoxef sodium
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
orl-man TDLo:571 mg/kg/20D-I:GIT |
JAMAAP JAMA, Journal of the American Medical Association. 250 (1983),730. | ||
2. |
ivn-man LDLo:371 mg/kg/17D-I:BLD |
DICPBB Drug Intelligence and Clinical Pharmacy. 18 (1984),140. | ||
3. |
ivn-man TDLo:1143 mg/kg/10D-I:BLD |
DICPBB Drug Intelligence and Clinical Pharmacy. 18 (1984),721. | ||
4. |
ipr-rat LD50:8100 mg/kg |
NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
5. |
scu-rat LD50:9000 mg/kg |
NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
6. |
ivn-rat LD50:5500 mg/kg |
NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
7. |
ipr-mus LD50:8100 mg/kg |
NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
8. |
scu-mus LD50:9000 mg/kg |
NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
9. |
ivn-mus LD50:5500 mg/kg |
NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. |
Consensus Reports:
SAFETY PROFILE:
Mildly toxic by several routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects: ulceration or bleeding from small and large intestine, hemorrhage, thrombocytopenia. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.
Hazard Codes:
Xn: Harmful
Risk Statements about Latamoxef sodium (64953-12-4):
R42/43: May cause sensitization by inhalation and skin contact.
Safety Statements about Latamoxef sodium (64953-12-4):
S22 Do not breathe dust.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.
Standards and Recommendations:
Analytical Methods:
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