CAS No.:98079-52-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	50mg/kg (50mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 32, Pg. 1288, 1990.
mouse	LD50	intravenous	253mg/kg (253mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 36(Suppl,
mouse	LD50	oral	1608mg/kg (1608mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 36(Suppl,
mouse	LD50	subcutaneous	995mg/kg (995mg/kg)		Zhongguo Kangshengsu Zazhi. Chinese Journal of Antibiotics. Vol. 19, Pg. 154, 1994.
rat	LD50	intravenous	328mg/kg (328mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 36(Suppl,
rat	LD50	oral	1556mg/kg (1556mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 36(Suppl,
rat	LD50	subcutaneous	1637mg/kg (1637mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 36(Supp

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes: Xn
Risk Statements: 22
 R22:Harmful if swallowed.
WGK Germany: 3
RTECS of Lomefloxacin hydrochloride (CAS NO.98079-52-8): VB1997500

Standards and Recommendations：

 

Analytical Methods：