CAS No.:71-58-9

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 5gm/kg (5000mg/kg)		Drugs in Japan Vol. -, Pg. 1196, 1990.
mouse	LD50	intraperitoneal	> 1500mg/kg (1500mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
mouse	LD50	oral	> 16gm/kg (16000mg/kg)	ENDOCRINE: ADRENAL CORTEX HYPOPLASIA	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
mouse	LD50	subcutaneous	> 1500mg/kg (1500mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
rat	LD50	intraperitoneal	> 900mg/kg (900mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
rat	LD50	oral	> 6400mg/kg (6400mg/kg)	LIVER: OTHER CHANGES	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
rat	LD50	subcutaneous	> 900mg/kg (900mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
women	TDLo	intravenous	10mg/kg (10mg/kg)	SENSE ORGANS AND SPECIAL SENSES: INCREASED INTRAOCULAR PRESSURE: EYE	Advances in Planned Parenthood. Vol. 8, Pg. 103, 1972.
women	TDLo	intravenous	21mg/kg (21mg/kg)	SENSE ORGANS AND SPECIAL SENSES: INCREASED INTRAOCULAR PRESSURE: EYE	Advances in Planned Parenthood. Vol. 8, Pg. 103, 1972.

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes: Xn
Risk Statements: 40-48 
R40: Limited evidence of a carcinogenic effect
R48: Danger of serious damage to health by prolonged exposur
Safety Statements: 22-36/37/39-45 
S22: Do not breathe dust
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection

S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: TU5010000

Standards and Recommendations：

 

Analytical Methods：