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Current position:Home > Products > Methylprednisolone acetate

CAS No.:53-36-1

Name: Methylprednisolone acetate

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 1409mg/kg (1409mg/kg)   Drugs in Japan Vol. -, Pg. 1182, 1990.
mouse LD50 subcutaneous 1320mg/kg (1320mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: OTHER CHANGES
Journal of Toxicological Sciences. Vol. 10(Suppl,
rat LD50 oral > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. -, Pg. 1182, 1990.
rat LD50 subcutaneous 265mg/kg (265mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: OTHER CHANGES
Journal of Toxicological Sciences. Vol. 10(Suppl,


Consensus Reports:

 


SAFETY PROFILE:

Poison by subcutaneous route. Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it yields acrid smoke and fumes.


Standards and Recommendations:

 


Analytical Methods:

 


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