CAS No.:53-36-1
Name: Methylprednisolone acetate
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | > 1409mg/kg (1409mg/kg) | Drugs in Japan Vol. -, Pg. 1182, 1990. | |
| mouse | LD50 | subcutaneous | 1320mg/kg (1320mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES |
Journal of Toxicological Sciences. Vol. 10(Suppl, |
| rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Drugs in Japan Vol. -, Pg. 1182, 1990. | |
| rat | LD50 | subcutaneous | 265mg/kg (265mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES |
Journal of Toxicological Sciences. Vol. 10(Suppl, |
Consensus Reports:
SAFETY PROFILE:
Poison by subcutaneous route. Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it yields acrid smoke and fumes.
Standards and Recommendations:
Analytical Methods:
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