CAS No.:21087-64-9
Name: Metribuzin
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LD50 | oral | > 500mg/kg (500mg/kg) | "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A280, Pg. 1983, | |
guinea pig | LD50 | oral | 250mg/kg (250mg/kg) | "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976. | |
mouse | LC | inhalation | > 860mg/m3/4H (860mg/m3) | "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 6, Pg. 1042, 1991. | |
mouse | LD50 | intraperitoneal | 210mg/kg (210mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Pesticide Biochemistry and Physiology. Vol. 23, Pg. 123, 1984. |
mouse | LD50 | oral | 564mg/kg (564mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 127, 1987. | |
mouse | LD50 | skin | > 1gm/kg (1000mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 127, 1987. | |
mouse | LD50 | subcutaneous | 367mg/kg (367mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 127, 1987. | |
quail | LD50 | oral | 164mg/kg (164mg/kg) | Pesticide Manual. Vol. 8, Pg. 573, 1987. | |
quail | LD50 | unreported | 168mg/kg (168mg/kg) | Farm Chemicals Handbook. Vol. -, Pg. C204, 1991. | |
rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Farm Chemicals Handbook. Vol. -, Pg. C204, 1991. | |
rat | LC50 | inhalation | > 860mg/m3/4H (860mg/m3) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 127, 1987. | |
rat | LD50 | intraperitoneal | 239mg/kg (239mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 127, 1987. | |
rat | LD50 | oral | 1100mg/kg (1100mg/kg) | Farm Chemicals Handbook. Vol. -, Pg. C204, 1991. | |
rat | LD50 | skin | 2gm/kg (2000mg/kg) | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1001, 1986. | |
rat | LD50 | subcutaneous | 814mg/kg (814mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 127, 1987. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion and intraperitoneal routes. Low toxicity by skin contact. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Hazard Codes: Xn,N,F
Risk Statements: 22-50/53-36-20/21/22-11
R22:Harmful if swallowed.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R36:Irritating to eyes.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R11:Highly flammable.
Safety Statements: 2-60-61-36-26-16
S2:Keep out of the reach of children.
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S36:Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S16:Keep away from sources of ignition.
RIDADR: UN3077 9/PG 3
RTECS: XZ2990000
Standards and Recommendations:
Analytical Methods:
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