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CAS No.:85622-95-3

Name: Mitozolomide

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

dnd-hmn:emb 50 µmol/L

    CNREA8    Cancer Research. 44 (1984),1772.
2.    

dnd-mus:leu 50 µmol/L

    CNREA8    Cancer Research. 44 (1984),1767.
3.    

orl-hmn TDLo:3108 µg/kg:GIT,BLD

    BJCAAI    British Journal of Cancer. 55 (1987),433.
4.    

ipr-mus LD10: 45 mg/kg

    BJCAAI    British Journal of Cancer. 58 (1988),139.

Consensus Reports:

 


SAFETY PROFILE:

Poison by intraperitoneal route. Human systemic effects by ingestion: nausea or vomiting and blood changes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx and Cl.


Standards and Recommendations:

 


Analytical Methods:

 


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