CAS No.:128-53-0

TOXICITY DATA with REFERENCE：

1.		dni-hmn:oth 6 µmol/L		CNREA8    Cancer Research. 40 (1980),1414.
2.		dni-mus:oth 300 µmol/L		BBRCA9    Biochemical and Biophysical Research Communications. 106 (1982),1448.
3.		dni-mus:oth 6 µmol/L		CNREA8    Cancer Research. 40 (1980),1414.
4.		dni-ham:lng 750 nmol/L		32YWA5    Radiation Research, Biomedical, Chemical, and Physical Perspectives ,Nygaard, O.F., et al., ed.,New York, NY.: Academic,1975,742.
5.		ipr-rat LDLo:17 mg/kg		JMCMAR    Journal of Medicinal Chemistry. 15 (1972),534.
6.		ipr-mus LD50:25 mg/kg		NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. AD277-689 .

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Poison by intraperitoneal route. Human mutation data reported. Vapors are highly irritating. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:  T+ 
Risk Statements:  21-28-34-43-20/21 
R21:Harmful in contact with skin. 
R28:Very toxic if swallowed. 
R34:Causes burns. 
R43:May cause sensitization by skin contact. 
R20/21:Harmful by inhalation and in contact with skin.
Safety Statements:  26-28-36/37/39-45-28
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
R45:May cause cancer. 
R28:Very toxic if swallowed.  
RIDADR:  UN 2928 6.1/PG 2
WGK Germany:  3
RTECS:  UX9625000
F:  19
HazardClass:  6.1
PackingGroup:  II

Standards and Recommendations：

 

Analytical Methods：