CAS No.:1477-57-2
Name: N,N'-bis(dichloroacetyl)-1,8-diaminooctane
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| man | TDLo | oral | 943mg/kg/50D (943mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING | "Agents Affecting Fertility, a Symposium, 1964," Austin, C.R., and J.S. Perry, eds., Boston, Little, Brown & Co., 1965Vol. -, Pg. 93, 1965. |
| mouse | LD50 | oral | > 16gm/kg (16000mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 715, 1960. | |
| mouse | LDLo | intraperitoneal | 150mg/kg (150mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972. |
Consensus Reports：
EPA Genetic Toxicology Program.
SAFETY PROFILE：
Safety Statements of N,N'-bis(dichloroacetyl)-1,8-diaminooctane (CAS NO.1477-57-2): 24/25
S24/25: Avoid contact with skin and eyes.
Poison by intraperitoneal route. Human systemic effects by ingestion: nausea and vomiting. Human reproductive effects by ingestion: changes in spermatogenesis. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
Standards and Recommendations：
Analytical Methods：
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