CAS No.:55981-09-4
Name: Nitazoxanide
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cat | LD | oral | > 10gm/kg (10000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA |
JAT, Journal of Applied Toxicology. Vol. 5, Pg. 49, 1985. |
| dog | LD | oral | > 10gm/kg (10000mg/kg) | AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)" | JAT, Journal of Applied Toxicology. Vol. 5, Pg. 49, 1985. |
| mouse | LD50 | oral | 1350mg/kg (1350mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS |
JAT, Journal of Applied Toxicology. Vol. 5, Pg. 49, 1985. |
| rat | LD50 | oral | > 10gm/kg (10000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS |
JAT, Journal of Applied Toxicology. Vol. 5, Pg. 49, 1985. |
Consensus Reports:
SAFETY PROFILE:
Adverse effects of Nitazoxanide (CAS NO.55981-09-4):
Side effects are mostly gastrointestinal, include abdominal pain, headache, vomiting, nausea and diarrhea.
Standards and Recommendations:
Analytical Methods:
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