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PYRUVALDEHYDE

TOXICITY DATA with REFERENCE
1.    

eye-rbt 403 mg

    AJOPAA    American Journal of Ophthalmology. 29 (1946),1363.
2.    

mmo-sat 10 µg/plate

    ENMUDM    Environmental Mutagenesis. 8 (1986),9.
3.    

dns-rat-orl 300 mg/kg

    CRNGDP    Carcinogenesis. 6 (1985),91.
4.    

dnd-ham:ovr 1500 µmol/L

    CRNGDP    Carcinogenesis. 6 (1985),683.
5.    

sce-ham:ovr 100 µmol/L

    MUREAV    Mutation Research. 144 (1985),189.
6.    

orl-rat LD50:1165 mg/kg

    EESADV    Ecotoxicology and Environmental Safety. 2 (1978),369.
7.    

ipr-mus LD50:179 mg/kg

    NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .
Consensus Reports
IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 51 ,1991,p. 443.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 51 ,1991,p. 443.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Available Data IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 51 ,1991,p. 443.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.
SAFETY PROFILE

Poison by intraperitoneal route. Moderately toxic by ingestion. An eye irritant. Mutation data reported. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and irritating fumes.

Hazard Codes:  Xn,Xi
Risk Statements:  22-36
Safety Statements:  26-36
Hazard Note:  Irritant
Hazardous Substances Data: 78-98-8(Hazardous Substances Data)
.

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