CAS No.:58-13-9
Name: Phencarbamide hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intravenous | > 20mg/kg (20mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
mouse | LD50 | intravenous | 32mg/kg (32mg/kg) | AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)" | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 151, Pg. 515, 1964. |
mouse | LD50 | subcutaneous | 103mg/kg (103mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
rabbit | LD50 | intravenous | > 20mg/kg (20mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
rat | LD50 | intravenous | 33mg/kg (33mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
rat | LD50 | oral | 410mg/kg (410mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
rat | LD50 | subcutaneous | 400mg/kg (400mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. |
Consensus Reports:
SAFETY PROFILE:
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. When Phencarbamide hydrochloride (CAS NO.58-13-9) is heated to decomposition, it emits toxic fumes of SOx, NOx, and HCl. See also CARBAMATES and ESTERS.
Standards and Recommendations:
Analytical Methods:
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