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Current position:Home > Products > Phenobarbital sodium

CAS No.:57-30-7

Name: Phenobarbital sodium

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

dnr-esc 400 µg/well

    ENMUDM    Environmental Mutagenesis. 3 (1981),429.
2.    

msc-mus:lym 5 mmol/L

    MUREAV    Mutation Research. 110 (1983),147.
3.    

orl-man TDLo:36 mg/kg:CNS,GIT

    BMJOAE    British Medical Journal. 1 (1955),1238.
4.    

orl-rat LD50:150 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 138 (1962),224.
5.    

ipr-rat LD50:152 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 33 (1983),1155.
6.    

scu-rat LD50:195 mg/kg

    NYKZAU    Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 56 (1960),377.
7.    

ivn-rat LD50:83 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 8 (1965),220.
8.    

idu-rat LDLo:100 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 25 (1975),1037.
9.    

orl-mus LD50:200 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 127 (1959),318.
10.    

ipr-mus LD50:123 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 87 (1946),265.
 

Consensus Reports:

IARC Cancer Review: Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 13 ,1977,p. 157.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.


SAFETY PROFILE:

Hazard Codes  VeryT+
Risk Statements 25-40-43 
R25 :Toxic if swallowed. 
R40:Limited evidence of a carcinogenic effect. 
R43:May cause sensitization by skin contact.
Safety Statements 22-36/37/39-45
S22:Do not breathe dust. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RIDADR UN 2811 6.1/PG 3
WGK Germany -
RTECS CQ7000000
HazardClass 6.1(b)
PackingGroup III
 

 


Standards and Recommendations:

 


Analytical Methods:

 


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