CAS No.:57-30-7
Name: Phenobarbital sodium
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
dnr-esc 400 µg/well |
ENMUDM Environmental Mutagenesis. 3 (1981),429. | ||
2. |
msc-mus:lym 5 mmol/L |
MUREAV Mutation Research. 110 (1983),147. | ||
3. |
orl-man TDLo:36 mg/kg:CNS,GIT |
BMJOAE British Medical Journal. 1 (1955),1238. | ||
4. |
orl-rat LD50:150 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 138 (1962),224. | ||
5. |
ipr-rat LD50:152 mg/kg |
ARZNAD Arzneimittel-Forschung. Drug Research. 33 (1983),1155. | ||
6. |
scu-rat LD50:195 mg/kg |
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 56 (1960),377. | ||
7. |
ivn-rat LD50:83 mg/kg |
JMCMAR Journal of Medicinal Chemistry. 8 (1965),220. | ||
8. |
idu-rat LDLo:100 mg/kg |
ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1037. | ||
9. |
orl-mus LD50:200 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 127 (1959),318. | ||
10. |
ipr-mus LD50:123 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 87 (1946),265. | ||
Consensus Reports:
IARC Cancer Review: Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 13 ,1977,p. 157.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
SAFETY PROFILE:
Hazard Codes T+
Risk Statements 25-40-43
R25 :Toxic if swallowed.
R40:Limited evidence of a carcinogenic effect.
R43:May cause sensitization by skin contact.
Safety Statements 22-36/37/39-45
S22:Do not breathe dust.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RIDADR UN 2811 6.1/PG 3
WGK Germany -
RTECS CQ7000000
HazardClass 6.1(b)
PackingGroup III
Standards and Recommendations:
Analytical Methods:
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