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CAS No.:553-69-5

Name: Phenylramidol

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Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 355mg/kg (355mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANTIPSYCHOTIC

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 141, Pg. 83, 1963.
mouse LD50 intravenous 124mg/kg (124mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Archives Internationales de Pharmacodynamie et de Therapie. Vol. 141, Pg. 83, 1963.
mouse LD50 oral 1850mg/kg (1850mg/kg)   Bollettino Chimico Farmaceutico. Vol. 103, Pg. 245, 1964.
mouse LD50 subcutaneous 405mg/kg (405mg/kg) BEHAVIORAL: ANTICONVULSANT Acta Pharmacologica et Toxicologica. Vol. 19, Pg. 247, 1962.
rat LD50 oral 756mg/kg (756mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANTIPSYCHOTIC

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 130, Pg. 280, 1961.


Consensus Reports:

 


SAFETY PROFILE:

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When Phenylramidol (CAS NO.553-69-5) is heated to decomposition ,it emits toxic fumes of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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