CAS No.:2255-17-6
Name: Phosphoric acid, dimethyl-4-nitro-m-tolyl ester
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
chicken | LD50 | oral | 35mg/kg (35mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Bochu Kagaku. Scientific Pest Control. Vol. 40, Pg. 49, 1975. |
guinea pig | LD50 | intravenous | 32mg/kg (32mg/kg) | Agricultural and Biological Chemistry. Vol. 27, Pg. 669, 1963. | |
guinea pig | LD50 | intravenous | 32mg/kg (32mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Agricultural and Biological Chemistry. Vol. 27, Pg. 669, 1963. |
guinea pig | LD50 | oral | 221mg/kg (221mg/kg) | Agricultural and Biological Chemistry. Vol. 27, Pg. 669, 1963. | |
guinea pig | LD50 | oral | 221mg/kg (221mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Agricultural and Biological Chemistry. Vol. 27, Pg. 669, 1963. |
mouse | LD50 | intracrebral | 19600ng/kg (0.0196mg/kg) | Pesticide Biochemistry and Physiology. Vol. 8, Pg. 302, 1978. | |
mouse | LD50 | intraperitoneal | 2700ug/kg (2.7mg/kg) | Pesticide Biochemistry and Physiology. Vol. 8, Pg. 302, 1978. | |
mouse | LD50 | oral | 20mg/kg (20mg/kg) | Actualites Pharmacologiques. Vol. 16, Pg. 7, 1963. | |
mouse | LD50 | unreported | 120mg/kg (120mg/kg) | Bulletin of the World Health Organization. Vol. 44, Pg. 31, 1971. | |
rat | LD50 | intravenous | 3300ug/kg (3.3mg/kg) | Agricultural and Biological Chemistry. Vol. 27, Pg. 669, 1963. | |
rat | LD50 | intravenous | 3300ug/kg (3.3mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Agricultural and Biological Chemistry. Vol. 27, Pg. 669, 1963. |
rat | LD50 | oral | 24mg/kg (24mg/kg) | Agricultural and Biological Chemistry. Vol. 27, Pg. 669, 1963. | |
rat | LD50 | oral | 24mg/kg (24mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Agricultural and Biological Chemistry. Vol. 27, Pg. 669, 1963. |
women | TDLo | oral | 2mL/kg (2mL/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: CYANOSIS |
Japanese Journal of Toxicology. Vol. 6, Pg. 197, 1993. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion, intravenous, and intraperitoneal routes. When Phosphoric acid, dimethyl-4-nitro-m-tolyl ester (CAS NO.2255-17-6) is heated to decomposition, it emits very toxic fumes of NOx and POx. See also ESTERS.
RIDADR 3018
HazardClass 6.1(a)
PackingGroup II
Standards and Recommendations:
Analytical Methods:
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