CAS No.:17617-45-7
Name: Picrotoxinin
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | subcutaneous | 1100ug/kg (1.1mg/kg) | "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931. | |
frog | LDLo | subcutaneous | 1100ug/kg (1.1mg/kg) | "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931. | |
mouse | LD50 | intracrebral | 10ug/kg (0.01mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology Letters. Vol. 60, Pg. 289, 1992. |
mouse | LD50 | intraperitoneal | 8980ug/kg (8.98mg/kg) | Current Toxicology. Vol. 1, Pg. 199, 1993. | |
mouse | LDLo | subcutaneous | 1600ug/kg (1.6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of the American Pharmaceutical Association. Vol. 23, Pg. 98, 1934. |
pigeon | LDLo | intramuscular | 1600ug/kg (1.6mg/kg) | Journal of the American Pharmaceutical Association. Vol. 23, Pg. 98, 1934. | |
pigeon | LDLo | subcutaneous | 1600ug/kg (1.6mg/kg) | "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931. | |
rabbit | LDLo | subcutaneous | 1350ug/kg (1.35mg/kg) | "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931. |
Consensus Reports:
SAFETY PROFILE:
Poison by subcutaneous, intracerebral, and intramuscular routes. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Information of Picrotoxinin (CAS NO.17617-45-7):
Hazard Codes: T+
Risk Statements: 25-28
25: Toxic if swallowed
28: Very Toxic if swallowed
Safety Statements: 13-20-45-36/37-28
13: Keep away from food, drink and animal feeding stuffs
20: When using, do not eat or drink
28: After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36: Wear suitable protective clothing
37: Wear suitable gloves
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
Standards and Recommendations:
Analytical Methods:
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